|
Author/Editor |
Title |
Source |
Year |
|
KO, J.K.S. & CHO, C.H. |
Adaptive cytoprotection and the brain-gut axis |
Digestion, 83(Suppl.1):19-24 |
2011 |
|
KO, J.K.S., AUYEUNG, K.K.W. & LAW, P.C. |
Astragalus saponins: the multiple-targeting
anticarcinogenic and antimetastatic agent in combating colon cancers |
In: The Proceedings and Program Book of ISREC
Symposium 2011, Hallmarks and Horizons of Cancer, September 7-10, 2011;
Lausanne, Switzerland. p.111 |
2011 |
|
WONG, H.P., HO, J.W., KOO, M.W., YU, L., WU, W.K.,
LAM, E.K., TAI, E.K., KO, J.K.,
SHIN, V.Y., CHU, K.M. & CHO, C.H. |
Effects of adrenaline in human colon adenocarcinoma
HT-29 cells |
Life Sciences, 88(25-26):1108-1112 |
2011 |
|
KO, J.K.S. & LEUNG,
C.C.Y. |
Ginger extract and polaprezinc exert gastroprotective actions by
antioxidant and growth factor modulating effects in rats |
Journal of Gastroenterology and Hepatology, 25:1861-1869 |
2010 |
|
AUYEUNG, K.K.W. & KO, J.K.S. |
Novel herbal flavonoids promote apoptosis but differentially induce cell
cycle arrest in human colon cancer cell |
Investigational New Drugs, 28:1-13 |
2010 |
|
KO, J.K.S., AUYEUNG,
K.K.W. & LAW, P.C. |
The synergistic antitumorigenic effects of vinblastine and total
Astragalus saponins (AST) with reduced invasiveness of colon cancer
cells |
European Journal of Cancer, 8 (7 Suppl.), 138. (22nd EORTC-NCI-AACR
Symposium on ¡¥Molecular Targets and Cancer Therapeutics¡¦, co-organized
by the American Association for Cancer Research, November 16-19, 2010;
Berlin, Germany) |
2010 |
|
AUYEUNG, K.K., CHO, C.H. & KO, J.K.S. |
A novel anticancer effect of Astragalus saponins: transcriptional
activation of NSAID-activated gene |
International Journal of Cancer, 125:1082-1091 |
2009 |
|
AUYEUNG, K.K.W., LAW, P.C. & KO, J.K.S. |
Astragalus saponins induces apoptosis via an ERK-independent NF-kB
signaling pathway in the human hepatocellular HepG2 cell line |
International Journal of Molecular Medicine, 23:189-196. |
2009 |
|
AUYEUNG, K.K.W. & KO, J.K.S. |
Coptis chinensis inhibits hepatocellular carcinoma cell growth through
nonsteroidal anti-inflammatory drug-activated gene activation |
International Journal of Molecular Medicine, 24:571-577 |
2009 |
|
KO, J.K.S. & AUYEUNG,
K.K.W. |
Molecular targeting of phytochemicals in gastrointestinal cancers |
Journal of Physiology and Pharmacology 60 (Suppl. 2), 45. (13th
International Conference on Gastrointestinal Research and 13th
International Conference on Ulcer Research, September 10-16; Split,
Croatia) |
2009 |
|
KO, J.K.S. |
Profiling of the action mechanisms and molecular targets of novel
chemotherapeutics derived from herbal source in gastrointestinal cancers |
In: The Programme Book of the BIT¡¦s 2nd Annual World Cancer Congress
2009, June 22-25, 2009; Beijing, China. p.87 |
2009 |
|
KO, J.K.S. & CHIK,
C.W.S. |
The protective action of radix Astragalus membranaceus against hapten-induced
colitis through modulation of cytokines |
Cytokine, 47:85-90. |
2009 |
|
KO, J.K.S., MOK, N.L.,
WONG, C.M. & AUYEUNG, K.K.W. |
Astragalus saponins (AST) modulate mTOR and ERK signaling with NF-kappa
B as target in native and cytokine-induced HT-29 colon cancer cells |
European Journal of Cancer 6 (12 Suppl.), 179-180. (20th EORTC-NCI-AACR
Symposium on ¡¥Molecular Targets and Cancer Therapeutics¡¦, co-organized
by the American Association for Cancer Research, October 21-24, 2008;
Geneva, Switzerland) |
2008 |
|
KO, J.K.S. & AUYEUNG,
K.K.W. |
Astragalus saponins induce apoptosis in human gastric adenocarcinoma
cells via a caspase 3-dependent pathway |
Journal of Shenyang Pharmaceutical University, 25 (Suppl.), 6 ;
Symposium between Mainland and Hong Kong on Pharmacology and Clinical
Pharmacology, October 10-13, 2008; Shenyang, China |
2008 |
|
KO, J.K.S. & AUYEUNG,
K.K.W. |
Herbal (Astragalus) saponins inhibit HepG2 cell growth and promote
apoptosis through NF-kB and ERK signaling |
In: Proceedings of the 99th Annual Meeting of the American Association
for Cancer Research 2008, April 12-16, 2008; San Diego, California,
U.S.A. Abstract no. 2276 |
2008 |
|
Auyeung, K. K. W., P. L. Liu, C. Chan, W. Y. Wu, S. S. T. Lee &
J. K. S. Ko. |
Herbal Isoprenols Induce Apoptosis in Human Colon Cancer Cells through
Transcriptional Activation of PPAR Gamma |
Cancer Investigation, 26:708-717 |
2008 |
|
KO, J.K.S |
Radix Astragali extract as potential anti-carcinogenic agent: from
pro-apoptotic activity to identification of molecular targets |
In: The Programme and Abstract Book of the International Symposium on
Gastrointestinal Inflammation and Cancer: from Etiology to Therapy,
September 26-28, 2008; Beijing, China. p.30-31 |
2008 |
|
TIN, M.M.Y., CHO, C.H., CHAN, K., JAMES, A.E. & KO,
J.K.S. |
Astragalus saponins induce growth inhibition and apoptosis in human
colon cancer cells and tumor xenograft |
Carcinogenesis, 28(6):1347-1355 |
2007 |
|
KO, J. K. S., AUYEUNG,
K.K.W., TIN, M.M.Y. & CHO, C.H. |
Astragalus Saponins Induce Transcriptional Activation of NSAID-Activated
Gene (NAG-1) in Colon Cancer Cells Via a PI3K-Akt/Egr-1 Signaling
Pathway |
Gastroenterology, 132 (Suppl.):A423 |
2007 |
|
KO, J.K.S., LEUNG,
W.C., HO, W.K. & CHIU, P. |
Herbal diterpenoids induce growth arrest and apoptosis in colon cancer
cells with increased expression of the nonsteroidal anti-inflammatory
drug-activated gene |
European Journal of Pharmacology, 559:1-13 |
2007 |
|
KO, J.K.S., TIN,
M.M.Y., CHO, C.H. & CHAN, K.K.C. |
Astragalus Saponins Induce Inhibition of Cell Proliferation in
Association with COX-Independent Overexpression of NAG-1 in Colon Cancer
Cells |
Gastroenterology, 130(Suppl. 2):A583 |
2006 |
|
KO, J.K.S., CHO, C.H.
& CHAN, K.K.C. |
A Comparative Study of the Antitumor Effects of a Novel Herbal Extract
and 5-Fu/oxaliplain in a Colon Tumor Xenograft Model |
Gastroenterology, 128(Suppl. 2):A178 |
2005 |
|
KO, J.K.S., LAM,
F.Y.L. & CHEUNG, A.P.L. |
Amelioration of experimental colitis by Astragalus membranaceus through
anti-oxidation and inhibition of adhesion molecule synthesis |
World Journal of Gastroenterology, 11 (37):5787-5794 |
2005 |
|
CHO, C.H. & KO, J.K.S. |
Herbal medicines and animal models of gastrointestinal diseases |
In: S. Gad (ed.) Drug Discovery Handbook. John Wiley & Sons: Hoboken,
U.S.A. Chapter 22, pp.1013-1035 |
2005 |
|
KO, J.K.S. & CHO, C.H. |
The diverse actions of nicotine and different extracted fractions from
tobacco smoke against hapten-induced colitis in rats |
Toxicological Sciences, 87(1):285-295 |
2005 |
|
KO, J.K.S. |
A Preliminary Study of the Effects of Astragali Radix Extract on
Apoptosis and Immunomodulation in Human Colonic Cancer Cells |
Journal of Leukocyte Biology, Suppl 2004:56-57 |
2004 |
|
KO, J.K.S.,
CHO, C.H. & LAM, S.K. |
Adaptive cytoprotection through modulation of nitric oxide in
ethanol-evoked gastritis |
World Journal of Gastroenterology 10, 2503-2508. |
2004 |
|
KO, J.K.S. |
Amelioration of Hapten-Induced Colitis by Radix Astragalus Membranaceus
through Modulation of Cytokines |
Toxicology and Applied Pharmacology, 197:344. |
2004 |
|
CHO, C.H., KO, J.K.S.
& KOO, M.W.L. |
Perspective and clinical significance of eicosanoids in the digestive
system |
In: P. Curtis-Prior (ed.) The Eicosanoids. John Wiley & Sons: London.
Chapter 36, pp.407-414 |
2004 |
|
KO, J.K.S. & C.H. CHO |
A Preliminary Study of the Immunomodulation by Radix Angelica Sinensis
(Chinese Dangguai) and Heparin in Experimental Colitis |
Gastroenterology, 124(Suppl.):A494-495 |
2003 |
|
LUK, H.H., KO, J.K.,
FUNG, H.S. & CHO, C.H. |
Delineation of the protective action of zinc sulfate on ulcerative
colitis in rats |
European Journal of Pharmacology 443, 197-204 |
2002 |
|
GUO, X., KO, J.K.S.,
MEI, Q.B. & CHO, C.H. |
Aggravating effect of cigarette smoke exposure on experimental colitis
is associated with leukotriene B4 and reactive oxygen metabolites |
Digestion 63, 180-187 |
2001 |
|
KO, J.K.S.,
SHAM, N.F., GUO, X. & CHO, C.H. |
Beneficial intervention of experimental colitis by passive cigarette
smoking through the modulation of cytokines in rats |
Journal of Investigative Medicine 49, 21-29 |
2001 |
|
GUO, X., LIU, E.S.L., KO, J.K.S.,
WONG, B.C.Y., YE, Y., LAM, S.K. & CHO, C.H. |
Protective role of cyclooxygenase inhibitor in the adverse action of
passive cigarette smoking on the initiation of experimental colitis in
rats |
European Journal of Pharmacology 411, 193-203 |
2001 |
|
KO, J.K.S. & CHO, C.H. |
Co-regulation of mucosal nitric oxide and prostaglandins in gastric
defensive mechanisms and their roles in adaptive cytoprotection |
Inflammation Research 48, 471-478 |
1999 |
|
GUO, X., WANG, W.P., KO, J.K.S.
& CHO, C.H. |
Involvement of neutrophils and free radicals in the potentiating effects
of passive cigarette smoking on inflammatory bowel disease in rats |
Gastroenterology, 117:884-892 |
1999 |
|
KO, J.K.S. & CHO, C.H. |
A histological study on the mechanisms of adaptive cytoprotection on
ethanol-induced mucosal damage
in rat
stomachs |
Digestive Diseases and Sciences 43, 1248-1257 |
1998 |
|
KO, J.K.S., MA, J.J.,
CHOW, J.Y.C. & CHO, C.H. |
The correlation of the weakening effect on gastric mucosal integrity by
5-HT with neutrophil activation |
Free Radical Biology and Medicine 24, 1007-1014 |
1998 |
|
KO, J.K.S., CHING,
C.K., CHOW, J.Y.C., ZHANG, S.T., LAM, S.K. & CHO, C.H. |
The vascular and glandular organoprotective properties of metronidazole
in the rodent stomach |
Alimentary Pharmacology and Therapeutics 11, 811-819 |
1997 |
|
KO, J.K.S. & CHO, C.H. |
Adaptive gastric mucosal cytoprotection in rats: different modes of
action by three mild irritants |
Digestion 57, 54-59 |
1996 |
|
KO, J.K.S. & CHO, C.H. |
The antilesion actions of anticholinergic agents on ethanol-induced
injury in rat stomachs: The importance of gastric vascular integrity and
tonicity |
Journal of Autonomic Pharmacology 16, 117-125 |
1996 |
|
KO, J.K.S. & CHO, C.H. |
Leucocyte-endothelial interactions in the vasculature following
inflammation of the gastric mucosa |
Journal of Gastroenterology and Hepatology 10, 469-470 |
1995 |
|
KO, J.K.S. & CHO, C.H. |
The mechanistic pathway of gastric adaptive cytoprotection: a study on
different components of the autonomic nervous system |
Journal of Autonomic Pharmacology 15, 205-214 |
1995 |
|
CHAN, Y.S., KO, J.K.S.
& CHO, C.H. |
The role of dorsal motor nucleus of vagus in gastric function and
mucosal damage induced by ethanol in rats |
Digestive Diseases and Sciences 40, 2312-2316 |
1995 |
|
KO, J.K.S. & CHO, C.H. |
The role of non-protein sulfhydryl compounds in gastric adaptive
cytoprotection against ethanol-induced mucosal damage in rats |
Inflammation Research 44, 242-244 |
1995 |