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| DR. ZHANG,
Huoming
(±i¤õ©ú) |
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B.Eng.; M.Sc. (Zhejiang University); M.Sc.
(Singapore-MIT Alliance); Ph.D., (National University of Singapore)
Research Assistant Professor
Department of Biology, Hong Kong Baptist University
Rm. T702; (852) 3411-5855
hmzhang@hkbu.edu.hk
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Current Research Interests:
- Proteomics technology and protein post-translational
modifications
- Immunology
- Cancer/Disease biomarkers
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CURRENT LABORATORY MEMBERS
- Liu Pei, postgraduate student (co-supervised by Dr Xia, Yi
Ji)
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SELECTED PUBLICATIONS
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Hao P, Zhang H, Sze SK. Application of Electrostatic
Repulsion Hydrophilic Interaction Chromatography (ERLIC) to the Characterization
of Proteome, Glycoproteome, and Phosphoproteome Using Nano LC-MS/MS. Methods
in Molecular Biology, Vol. 790 NanoProteomics. 2011, Sept (Book Chapter).
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Ye F, Zhang H, Yang YX, Hu HD, Sze SK, Meng W, Qian J,
Ren H, Yang BL, Luo MY, Wu X, Zhu W, Cai WJ, Tong JB. Comparative proteome
analysis of 3T3-L1 adipocyte differentiation using iTRAQ-coupled 2D LC-MS/MS.
Journal of Cellular Biochemistry. 2011 Jun 15. doi: 10.1002/jcb.23223.
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Zhang H, Wong YH, Wang H, Chen Z, Arellano SM, Ravasi
T, Qian PY. Quantitative proteomics identify molecular targets that are crucial
in larval settlement and metamorphosis of Bugula neritina. J Proteome Res
2011, Jan 7, 10(1): 349-60.
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Zhao C, Tan YC, Wong WC, Sem X, Zhang H, Han H, Sze SK,
Kourilsky P, Wong SC. The CD14+/lowCD16+ monocyte subset is more susceptible to
spontaneous and oxidant-induced apoptosis than the CD14+/highCD16- subset.
Cell Death & Disease. 2010, 1: e95. NOV 2010. doi: 10.1038/cddis.2010.69
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Zhang H, Guo T, Li X, Datta A, Yang J, Lim SK, Tam JP,
Sze SK. Simultaneous Characterization of Glyco- and Phosphoproteomes of Mouse
Brain Membrane Proteome with Electrostatic Repulsion Hydrophilic Interaction
Chromatography. Molecular & Cellular Proteomics. 2010 Apr; 9(4):635-47.
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Wang H, Zhang H, Wong YH, Voolstra C, Ravasi T,
Vladimir BV, Qian PY, Rapid transcriptome and proteome profiling of a non-model
marine invertebrate, Bugula neritina. Proteomics. 2010, 10(16), 2972-81.
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Zhang H, Zhao C, Li X, Zhu Y, Gan CS, Wang Y, Ravasi T,
Qian PY, Wong SC, Sze SK. Study of monocyte membrane proteome perturbation
during lipopolysaccharide-induced tolerance using iTRAQ-based quantitative
proteomic approach. Proteomics. 2010 Aug, 10 (15), 2780-9
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Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim
SK, Sze SK. Hypoxia modulates tumor microenvironment to enhance angiogenic and
metastastic potential by secretion of proteins and exosomes. Molecular &
Cellular Proteomics. 2010 Jun; 9(6): 1085-1099.
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Zhao C#; Zhang H#; Yeap WH; Gan CS; Sze SK; Kourilsky
P, Wong SC. Identification of Novel Functional Differences in Monocyte Subsets
Using Proteomic and Transcriptomic Methods. Journal of Proteome Research.
2009, 8(8), 4028-4038. #equal contribution.
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Guo T, Gan CS, Zhang H, Zhu Y, Oi Lian Kon, Sze SK,
Hybridization of Pulsed-Q Dissociation and Collision-Activated Dissociation in
Linear Ion Trap Mass Spectrometer for iTRAQ Quantitation, Journal of Proteome
Research, 2008, 7(11), 4831-4840.
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Meng W, Zhang H, Guo T, Chhiti Pandey, Yi Zhu, Oi Lian
Kon, Sze SK. One-step procedure for peptide extraction from in-gel digestion
sample for mass spectrometric analysis. Analytical Chemistry, 2008, 80
(24): 9797¡V9805.
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Zhang H, Lin QS, Ponnusamy S, Kothandaraman N, Lim TK,
Zhao CQ, Arijit B, Rauff M, Hew CL, Chung MCM, Joshi SB, Choolani M.
Differential recovery of membrane proteins after extraction by aqueous methanol
and trifluoroethanol. Proteomics. 2007. 7 (10), 1654-1663.
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| Dr. Zhang Huoming ¡@ |
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