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| DR. YUE, Ying
Kit (§E^³Ç) |
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B.Sc., Ph.D., Hong Kong Baptist University
Lecturer
Department of Biology, Hong Kong Baptist University
Rm. T1116; (852) 3411-5832
patrick@hkbu.edu.hk
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Current Research Interests:
- Pharmacological effect of Chinese medicines and natural products
- Angiomodulation study
- Research and development of high throughput screening platform for cell motility study
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RESEARCH PROJECTS
- Tumoricidal effects of Panax Ginseng on nasopharyngeal
carcinoma. (Co-I: Prof. Ricky NS
Wong). Source: FRG/ HKBU. Duration: 01/2010-12/2011.
- The anti-angiogenic activities of indirubin derivatives
(indirubin-3¡¦-oxime and E804)(Co-I: Dr. Kelvin SY Leung/ Shi Jue).
Source: FRG/ HKBU. Duration: 01/2010-12/2011.
- Molecular Biology / Introduction to Biotechnology -
Multimedia Education Packages for Studying Genetic Modified
Organisms. (Co-I: Prof. JH Zhang/ Ricky NS Wong/ NK Mak/ Chris
KC Wong/ YL Xia). Source: TDG/
HKBU. Duration: 01/2010-10/2013.
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SELECTED PUBLICATIONS
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Chan LY, Kwok HH, Chan RW, Peiris MJ, Mak NK, Wong RN, Chan
MC, Yue PY*. Dual functions of ginsenosides in protecting human
endothelial cells against influenza H9N2-induced inflammation and apoptosis. J Ethnopharmacol. 2011;137(3):1542-6.
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Yue PY, Leung EP, Mak NK, Wong RN. A simplified method
for quantifying cell migration/wound healing in 96-well plates. J Biomol Screen.
2010;15(4):427-33.
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Kwok HH, Ng WY, Yang MS, Mak NK, Wong RN, Yue PY*. The
ginsenoside protopanaxatriol protects endothelial cells from hydrogen
peroxide-induced cell injury and cell death by modulating intracellular redox
status. Free Radic Biol Med. 2010;48(3):437-45.
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Chan LS, Yue PY, Mak NK, Wong RN. Role of microRNA-214
in ginsenoside-Rg1-induced angiogenesis. Eur J Pharm Sci. 2009;38(4):370-7.
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CC Lau, WY Ha, PYK Yue, SH Chui, AKK Chui, RNS Wong. A
high throughput detection method for hepatitis B virus mutations in the Chinese
population. Hong Kong Medical Journal. 2008; 14(5): 4-7.
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PYK Yue, YK Cheng, NK Mak, KW Leung, AST Wong, TP Fan,
RNS Wong. Chapter 21 Ginseng and angiogenesis. Angiogenesis: Basic Science and
Clinical Application. 2007; 351-66.
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Leung KW, Yung KK, Mak NK, Yue PY, Luo HB, Cheng YK,
Fan TP, Yeung HW, Ng TB, Wong RN. Angiomodulatory and neurological effects of
ginsenosides. Curr Med Chem. 2007; 14(12):1371-80. Review.
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Yue PY, Mak NK, Cheng YK, Leung KW, Ng TB, Fan DT,
Yeung HW, Wong RN. Pharmacogenomics and the Yin/Yang actions of ginseng:
anti-tumor, angiomodulating and steroid-like activities of ginsenosides. Chin
Med. 2007; 15;2:6. Review.
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Lau CC, Yue PY, Chui SH, Chui AK, Yam WC, Wong RN.
Detection of single nucleotide polymorphisms in hepatitis B virus precore/basal
core promoter region by matrix-assisted laser desorption/ionization
time-of-flight mass spectrometry. Anal Biochem. 2007; 366(1):93-5.
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Lam HW, Lin HC, Lao SC, Gao JL, Hong SJ, Leong CW, Yue PY,
Kwan YW, Leung AY, Wang YT, Lee SM.The angiogenic effects of Angelica sinensis
extract on HUVEC in vitro and zebrafish in vivo. J Cell Biochem. 2008;
103(1):195-211.
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P Yue, DYL Wong, P.K. Wu, PY Leung, NK Mak, HW Yeung,
L. Liu, ZW Cai, ZH Jiang, TPD Fan, Ricky N.S. Wong. The angiosuppressive effects
of ginsenoside-Rg3. Biochem Pharmacol. 2006; 72(4):437-45.
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Fan TP, Yeh JC, Leung KW, Yue PY, Wong RN.
Angiogenesis: from plants to blood vessels. Trends Pharmacol Sci. 2006;
27(6):297-309. Review.
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WY Ha, XJ Li, PYK Yue, Daisy YL Wong, Kevin KM Yue, WS
Chung, L. Zhao, PY Leung, L. Liu, Ricky N.S. Wong. Gene expression profiling of
human synovial sarcoma cell line (Hs701.T) in response to IL-1b stimulation.
Inflamm Res. 2006; 55(7):293-9.
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Li XJ, Yue PY, Ha WY, Wong DY, Tin MM, Wang PX, Wong
RN, Liu L. Effects of the alkaloid sinomenine on gene expression of the
IL-1b-activated human synovial sarcoma cells. Life Sci. 2006; 79(7):665-73.
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Ha WY, Lau CC, Yue PY, Hung KK, Chan K, Chui SH, Chui
AK, Yam WC, Wong RN. Simultaneous detection of precore/basal core promoter
mutations in Hepatitis B virus using arrayed primer extension. Mol Diagn Ther.
2006; 10(2):125-34.
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Ha WY, Wu PK, Kok TW, Leung KW, Mak NK, Yue PY, Ngai
SM, Tsai SN, Wong RN. Involvement of PKC and E2F-5 in euxanthone-induced neurite
differentiation of neuroblastoma. Intl J Biochem Cell Biol. 2006; 38(8):
1393-1401.
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Zhao HY, Wong RNS, Fang KT, Yue PYK. Use of three-color
cDNA microarray experiments to assess the therapeutic and side effect of drugs
Chemometrics and Intelligent Laboratory Systems. (2006); 82:31-36.
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Yue PY, Wong DY, Ha WY, Fung MC, Mak NK, Yeung HW,
Leung HW, Chan K, Liu L, Fan TP, Wong RN. Elucidation of mechanisms underlying
the angiogenic effects of ginsenoside Rg1 in vivo and in vitro. Angiogenesis.
2005; 8(3):205-16.
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Liu L, Han L, Wong DY, Yue PY, Ha WY, Hu YH, Wang PX,
Wong RN. Effects of Si-Jun-Zi decoction polysaccharides on cell migration and
gene expression in wounded rat intestinal epithelial cells. Br J Nutr. 2005;
93(1), 21-29.
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Liu MJ, Yue PY, Wang Z, Wong RN. Methyl protodioscin
induces G2/M arrest and apoptosis in K562 cells with the hyperpolarization of
mitochondria. Cancer Lett. 2005; 224(2), 229-241.
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Kok TW, Yue PY, Mak NK, Fan TP, Liu L, Wong RN. The
anti-angiogenic effect of sinomenine. Angiogenesis. 2005; 8(1):3-12.
23. Zhao HY, Yue PY, Fang KT. Identification of differentially expressed genes
with Multivariate Outlier Analysis. J Biopharm Stat. 2004; 14(3):629-46.
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Zhao HY, Yue PY, Fang KT. Identification of
differentially expressed genes with Multivariate Outlier Analysis. J Biopharm
Stat. 2004; 14(3):629-46.
Book, and book chapters:
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PYK Yue*, Y Huang, RNS Wong. Ginsenoside Rg3 and Rh2:
the anti-cancer and anti-angiogenic saponins from ginseng.
¡§Anti-Angiogenesis-Drug Discovery and Development¡¨. volume1, issue 1, p34-57.
Bentham Science Publishers. 2010.
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PYK Yue* and RNS Wong. The Ginsenosides: Yin and Yang
in Angiogenesis. LAP LAMBERT Academic Publishing AG & Co. KG. 2009.
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PYK Yue*, YK Cheng, NK Mak, KW Leung, AST Leung, TP
Fan, RNS Wong. Chapter 21 Ginseng and angiogenesis. Angiogenesis: Basic Science
and Clinical Application. 2007; 351-66.
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Dr. Patrick YK Yue |
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